Home  >  Faculty  >  Nutrition Science  >  Huang, Ching-jane

 

 Chinese

Professor

Education¡DExperience¡DService¡DHonor¡DTeaching¡DResearch¡DPublication¡DResults

Huang,  Ching-jang   (AC2-409)

Tel 

3366-2276

2362-1301 (tel/fax)

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E-mail

cjjhuang@ntu.edu.tw

Web

Lab

Expertise

Nutrition

Metabolism  biochemistry

Molecular nutrition

Education

Doctor

National Taiwan University

Inst Agric Chem

1978/09 ~ 1984/06

Master

National Taiwan University

Inst Agric Chem

1976/09 ~ 1978/06

Bachelor

National Taiwan University

Dept Agric Chem

1972/09 ~ 1976/06

High school

Taipei Municipal First Girls¡¦ Senior High School

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1969/09 ~ 1972/06

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Experience

Dept Biochem Sci Tech (BST)

Professor and Director

Teaching & research

2003/08 ~ present

Inst Microbiol Biochem (mbc)

Professor

Teaching & research

2003/08 ~ present

Dept Agric Chem

Professor

Teaching & research

1990/08 ~ 2003/08

Karolinska Institute, Center for Biotechnology, Sweden

Visiting Scientist

Research

1996/08 ~ 1997/08

National Institute of Health, USA

Researcher

Research

1989/07 ~ 1990/06

Dept Agric Chem

Associate Professor

Teaching & research

1985/08 ~ 1990/07

Dept Agric Chem

Lecturer

Teaching & research

1985/03 ~ 1985/07

Dept Agric Chem

Teaching Assistant

Teaching & research

1984/03 ~ 1985/02

Colorado State Univ, Dept Food Science and Human Nutrition, USA

Visiting Scientist

Research

1984/03 ~ 1985/02

Rochester  University, USA  

 

Technician

1983/06 ~ 1984/01

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Service

Nutrition Society of Taiwan

  President

 

2006~2009

Science and Technology Review Board. Agriculture Council

  Committee Member

 

2006/7~2009/6

Dept Biochem Sci Tech (BST)

Director

 

2003/08 ~ present

Food Sanitary and Safety counsel committee, Department of Health, Taiwan

Member

 

2000 ~ present

The Promotion of the research and development of health/functional Foods, National Science Council, Department of Health and Department of Agriculture

Member of the Joint Committee

 

1999 ~ present

Nutrition Society of Taiwan

Secretary General

 

2001 ~ 2003

Committee for The revision of Dietary Reference Intake, Department of Health, Executive Yuan

Member of the Committee 

 

2000 ~ 2002

Journal of Food Science and Agricultural Chemistry

Associate editor

 

1999 ~ 2001

The study group of Nutritional Science, National Science Council, Taiwan

Chair

 

1998 ~ 2001

Journal of Chinese Agricultural Chemistry Society

Editor-in-Chief

 

1997 ~ 2001

10th Asian Congress of Nutrition

Secretary General

 

2003 ~ 2007

 

 

 

 

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Honor

International Postdoctoral Research Fellowship of John E. Fogarty Center, National Institute of Health, USA

1988

Publication #8 is awarded by American Oil Chemist Society as the annual outstanding paper in the "Protein and Co-product" section of the journal for the year

1988

Professor S.C. Chen Award for young outstanding nutritionist by Chinese Nutrition Society

1990

Research Award, National Science Council, Taipei, Taiwan

1991 ~ 2003

Outstanding Academic Research Award, Agricultural Chemistry Society of Taiwan

2003

Research Contribution Award, National Taiwan University

2004

Outstanding Research Contribution Award, Nutrition Society of Taiwan

2005

 

 

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Ou-wan-ta, 2007

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Current Teaching Course

Course Title

Credit

Loading

Period

Introduction to Food and  Nutrition

2

33%

 ~ present

Nutritional Chemistry and Nutrition Chemistry Lab.

3

33%

 ~ present

Vitamins

2

100%

 ~ present

Special Project

1

100%

 ~ present

Hormone & Signaling Molecules

2

100%

 ~ present

 Seminar

1

33%

 

 Courses for BST     Courses for mbc

Current Research Project

Project Title

Resource

Period

Research and development of yam and fermented soyfood to ameliorate metabolic syndrome

NSC

2006/08 ~ 2009/07

Identification of the phytoestrogenic compound in wild bitter gourd and its anti-metabolic syndrome effect in ovariectomized mice

NSC

2007/08 ~ 2008/12

Extraction and Identification of Momordica Charantia PPAR Activator and its Application as Insulin Sensitization/Lipid Lowering Dietary Supplement

NSC

2004/08 ~ 2007/07

Chemical identification and functional characterization of estrogenic compound/fraction in yam and screening of phytoestrogenic food materials

NSC

2003/08 ~ 2006/07

High fat diet-induced obesity and insulin resistance - Comparison between saturated and polyunsaturated fat

DOH

2004/08 ~ 2005/07

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Research Tools or platform

Detailed items

Ligand-dependent Transactivation Assay of  Nuclear Receptor

Assay for Peroxisome Proliferation Activated Receptors, Estrogen Receptors

Gene expression analysis

Northern blotting, Real Time RT PCR

Rodent model

Rat, mouse models for metabolic syndrome and estrogen deficiency

Cell culture

RAW264.7, CHO cell, 3T3-L1, C2C12, MCF-7, Ishikawa

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Research Systems

Description

Momordica charantia

Dioscorea alata

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Publication  1998~2008

Referred Papers

Huang, C.J., Feltkamp, D., Nilsson, S. and Gustafsson, J.A. (1998) Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signaling. Biochem. Biophys. Res. Commun. 243: 657-663

Shaw, H.M. and Huang, C.J. (1998) Liver alpha-tocopherol transfer protein and its mRNA were differentially altered by dietary vitamin E deficiency and protein insufficiency in rats. J. Nutr., 128: 2348-2354

´ö¶®²z¡B¶À«C¯u (1998) ¬µªo¶¼­¹­°§C¦å¼ß»P¨xŦºû¥Í¯À A §t¶q¡C¤¤µØÀç»x¡A23: 265-279

¦¶­õ½÷¡B¶À«C¯u (1998) ¶¼­¹¬µªo­°§C £]-­JÅÚ½³¯À¤§ºû¥Í¯À A ®Ä¤O¡C¤¤µØÀç»x¡A23: 281-295

Huang, C.j., Tang, Y.L., Chen, C.Y., Chen, M.L., Chu, C.H & Hseu, C.T. (2000) The bioavailability of b-carotene in stir- or deep-fried vegetables determined by measuring serum response to a single ingestion in men. J. Nutr. 130: 534-540

Shaw, H.M. and Huang, C.j. (2000) Secretion of a-tocopherol in VLDL was decreased by dietary protein insufficiency in young growing rats. J. Nutr. 130: 3050-3054

²ø¦ã¬Â¡B¼ï¤l©ú¡B¬x¼zµÓ¡B¶À«C¯u (2000) §t¹è¿}¶¼®Æ¹ï¤j¥Õ¹«¸z¹Dµß¬Û¤§¼vÅT¡C¤¤µØÀç»x¡A25 (4): 233-243

Wu, M.C. and Huang, C.j. (2001) Inhibition of prostaglandin E2 production of a macrophage cell line by some phytochemicals. Fd. Sci. Agric. Chem. 3: 59-71

»¯»_±Ó¡B¶À«C¯u (2001) 15-deoxy-£G12,14-PGJ2 ¹ï 3T3-L1 «e¯×ªÕ²Ó­M¤À¤Æ¤§¼vÅT¡C¤¤°êÂåÃĬì¾ÇÂø»x¡A2: 117-124

Chao, P.M., Chao, C.Y., Lin, F.J. and Huang, C.j. (2001) Oxidized frying oil up-regulates hepatic acyl CoA oxidase and cytochrome P-450 4A1 genes in rats and activate PPAR-a. J.Nutr.131: 3166-3174

Wu, M.C. and Huang, C.j. (2002) Differential effects of foods traditional regarded as heating and cooling on prostaglandin E2 production by a macrophage cell line. J. Biomed. Sci. 9: 596-606

¼B¬ÃªÚ¡B Àdµá²ú¡B ¤ý·O¶ê¡B³¯¥©©ú¡B¿½¹çÄÉ¡B°ª¬ü¤B¡B²ø¨Î¿o¡B¶À«C¯u (2002) ´¶³q¶¼­¹¤¤ºû¥Í¯À E¡BÖ´¡BÄqª«½è¤Î¤@¯ëÀç¾i¦¨¥÷¤ÀªR¡C¤¤µØÀç»x¡A27 (4): 221-231

Chao, C.Y. and Huang, C.-j (2003) Bitter gourd (Momordica charantia) extract activates PPAR and up-regulates the expression of acyl CoA oxidase gene in H4IIEC3 hepatoma cells. J Biomed Sci 10: 782-791

Chao, P.M., Hsu, S.C., Lin, F.J., Li, Y.J. and Huang, C.j (2004) The up-regulation of hepatic acyl-CoA oxidase and cytochrome  P450 4A1 mRNA expression by dietary oxidized frying oil is comparable between male and female rats. Lipids: 39: 233-238

Lin, S.Y., Chen W.Y., Lee F.Y., Huang, C.j., and Sheu, W.H.H. (2005) Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-a. Am J Physiol Endocrinol Metab 288: E493-E501

Lin, S.Y., Sheu, W.H.H., Chen W.Y., Lee F.Y., Huang, C.j. (2005) Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha. Mol. Cell. Endocrinol. 232: 1¡V8

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang, C.j. (2005)  Plasma Retinol and £\-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asian Pacific J. Clin. Nutr. 14(3): 256-262

Chao, P.M., Yang, M.F., Tseng, Y.N., Chang, K.M., Lu, K.S., Huang, C.j. (2005) Peroxisome proliferation in liver of rats fed oxidized frying oil. J. Nutr. Sci. Vitaminol. 51: 361-368

Lin, S.Y., Chen W.Y., Lee F.Y., Huang, C.j., and Sheu, W.H.H. (2005) Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-. Am J Physiol Endocrinol Metab 288: E493-E501

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang*, C-j. (2005)  Plasma Retinol and \-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asia Pac J Clin Nutr 2005; 14 (3):256-262

Chao, P.M., Yang, M.F., Tseng, Y.N., Chang, K.M., Lu, K.S., Huang*, C.-j. (2005) Peroxisome proliferation in liver of rats fed oxidized frying oil. J. Nutr. Sci. Vitaminol. 51: 361-368

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang*, C-j. (2005)  Plasma Retinol and \-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asia Pac J Clin Nutr 2005; 14 (3):256-262

Hsieh, C.C., Huang, C-j and Lin, B.F. (2006) Low and high levels of a-tocopherol exert opposite effects on IL-2 possibly through the modulation of PPARg, IkB and apoptotic pathway in activated splenocytes. Nutrition (Accepted)

Hsu, S-C, Huang, C.-j. (2006) Changes of Liver PPAR£\  mRNA Expression in Response to two levels of high safflower oil diets Correlated with Changes of Adiposity and serum leptin in rats and mice. J. Nutr. Biochem. (Published on-line)

Hsu, S-C, Huang, C.-j*. (2006) Reduced fat mass in rats fed a high oleic acid-rich safflower oil diet is associated with changes in expression of hepatic PPAR alpha and adipose SREBP-1c-regulated genes. J. Nutr. 1779-1785

Chia-Ying Chuang, Chin Hsu, Che-Yi Chao, Yung-Shung Wein, Yueh-Hsiung Kuo, Ching-jang Huang (2006) Fractionation and Identification of 9c, 11t, 13t- Conjugated Linolenic Acid as an Activator of PPARalpha in Bitter Gourd (Momordica charantia L.)  J Biomed Sci. 13(6):763-72.

Lun-Cheng Kuo, Wei-Yi Cheng, Ren-Yu Wu, Ching-Jang Huang and Kung-Ta Lee (2006) Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto. Applied Microbiology and Biotechnology 73(2):314-320.

Hsu, S-C, Huang, C.-j*. (2007) Changes of Liver PPARa mRNA Expression in Response to two levels of high safflower oil diets Correlate with Changes of Adiposity and serum leptin in rats and mice. J. Nutr. Biochem. 18(2), 86-96.

Pei-Min Chao, Hui-Ling Huang, Chun-Huei Liao, Shiau-Ting Huang, and Ching-jang Huang(2007) A high oxidized frying oil content diet is less adipogenic, but induces glucose intolerance in rodents. Br J Nutr. 2007 Jul;98(1):63-71. (SCI) (NSC 92-2320-B-039-027-)

Wei-Yi Cheng, Yueg-Hsiung Kuo and Ching-jang Huang*. "Isolation and Identification of Novel Estrogenic Compounds in Yam Tuber (Dioscorea alata cv. Tainung No.2)," J Agric Food Chem., vol.55, no.18, pp.7350-7358, 2007.09 (SCI)

Huang HL, Hong YW, Wong YH, Chen YN, Chyuan JH, Huang CJ, Chao PM*.(2008) Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats. British Journal of Nutrition. 99(2), 230-239. (SCI) (NSC 93-2317-B-039-004-)

Mark L Wahlqvist, Meei-Shyuan Lee, Joseph Lau, Ken N Kuo, Ching-jang Huang, Wen-Harn Pan, Hsing-Yi Chang, Rosalind Chen and Yi-Chen Huang*. Evidence-based nutrition (EBN) in the Asia Pacific region: clinical practice and policy-setting. Asia Pac J Clin Nutr 2008;17 (1):2-7 (SCI)

Yong-Han Hong, Tzu-Ching Wang, Ching-Jang Huang,Wei-Yi Cheng, and Bi-Fong Lin*. Soy isoflavones supplementation alleviates disease severity in autoimmune-prone MRL-lpr/lpr mice. Lupus. accepted. (SCI)

Yong-Han Hong, Ching-Jang Huang, Ssu-Ching Wang, and Bi-Fong Lin*. Alfalfa Sprout Extract in Ethyl Acetate Ameliorates Disease Severity of Autoimmune-Prone MRL-lpr/lpr Mice. Lupus. accepted. (SCI)

 

Conference Abstracts

§õ¥ç¿²¡B¶À«C¯u (2001) ¤ñ¸û¶À¨§ªo¡Bªãªáªo¤Î¤û¯×ªo¬µ«á¹ï¤j¹«¨xŦ¤¤ PPAR£\ ¤U´å°ò¦]¤Î Cytochrome P-450 ¦P¥\×Qªí²{¤§¼vÅT®ÄÀ³¡C¤¤µØ¥Á°êÀç¾i¾Ç·|²Ä 27 ©¡¦~·|º[¾Ç³N¬ã°Q·|¤â¥U, p104, 5 ¤ë 18-19 ¤é, ¥x¥_

¾GÞ³©y¡B¶À«C¯u (2001) ¶¼­¹¬µªo¹ï¤j¹«Å餺¤ô¤À¤Î¹[¶u¥­¿Å¤§¼vÅT¡C¤¤µØ¥Á°êÀç¾i¾Ç·|²Ä27©¡¦~·|º[¾Ç³N¬ã°Q·|¤â¥U, p113,  5 ¤ë 18-19 ¤é, ¥x¥_

Huang. C.j. (2001) Effect of high fat diets on the mRNA expression of PPAR-alpha and its target genes after fasting. Annals of Nutrition ¡® Metabolism , 17th International Congress of Nutrition, August 27-31, 2001, Vienna, Australia. Abstracts. p83

Huang. C.j. (2001) Annals of Nutrition ¡® Metabolism , 17th International Congress of Nutrition, August 27-31, 2001, Vienna, Australia. Abstracts. p389

Ching-Jang Huang (2001) PPAR and Atherosclerosis (PPAR »P°Ê¯ßµ°ª¬µw¤Æ)¡C¤¤µØ¥Á°ê¦å¯×¤Î°Ê¯ßµw¤Æ¾Ç·|90¦~«×¾Ç³N¬ã°Q·| ¤j·|·|¥Z, p33-34,  9 ¤ë 15 ¤é, ¥x¥_

¶À«C¯u (2001) ¼vÅT«e¦C¸¢¯À E2 ¥Í¦X¦¨¤§­¹ª«©Î­¹ª«¦¨¥÷¡C¤¤µØ¥Á°ê­¹«~¬ì§Þ¾Ç·|¦~·|¤Î¾÷¯à©Ê­¹«~¬ã°Q·|, 11 ¤ë 10-11 ¤é, ¹Å¸q

¶À«C¯u (2001) §C¼ö¶qªº¬P¬P¤ôªG - ·sÂA·¨®ç¡C«~µP¤ôªG - ·¨®ç¬ã°Q·|, °ê¥ß¥xÆW¤j¾Ç¹A·~³¯¦CÀ]¤Î¹A·~¤Æ¾Ç¨t¥D¿ì, p24-25, 12 ¤ë 14 ¤é, ¥x¥_

¶À«C¯u (2002) ¶¼­¹Àç¾i¦]¤l»P°ò¦]¤§¥æ¤¬§@¥Î - °ò¦²z½×»PÀ³¥Î¡C¡u°ò¦]¬ì§Þ»PÀç¾i«O°·¡v¬ã°Q·|, ¤¤µØ¥Á°êÀç¾i¾Ç·|¥D¿ì, p18-19, 3 ¤ë 28 ¤é, ¥x¥_

Huang, C.j*. (2003) Activation of Peroxisome Proliferator-Activated Receptor alpha by a polar fraction isolated from oxidized frying oil. Asian Congress of Nutrition, Feb.23-27, New Delhi, India, Abstracts. P86

Chao, CY, Kuo Y.H., Wein, Y.S. and Huang, C.J*. (2003) Activation of Peroxisome Proliferator Activating Receptor a by some compounds and extracts from food materials. Keystone Symposium. PPARs: Transcriptional Regulators of Metabolism and Metabolic Disease (B5) February 4 - 9, Keystone, Colorado, USA

»¯­õ¼Ý¡B¶À«C¯u* (2003) ­W¥Ê¬¡¤Æ PPAR ¤Î½Õ¸`¯×½è¥NÁ°ò¦]¤§ªí²{¡C¤¤µØ¥Á°êÀç¾i¾Ç·|²Ä29©¡¦~·| ¤¤µØÀç»x Vol.28. No.2, p17, 6¤ë, ¥x¥_

§õ©yÀR¡B²ø¨Î¿o¡B¶À«C¯u* (2003) ¶¼­¹ phytol ´£°ª¤j¹« PPAR£\ ¤U´å°ò¦] Acyl- CoA Oxidase ¤§¬¡©Ê¡C¤¤µØ¥Á°êÀç¾i¾Ç·| 29 ©¡¦~·| ¤¤µØÀç»x Vol.28. No.2, p26, 6 ¤ë, ¥x¥_

®}瑨¡B¶À«C¯u* (2003) ¬µªo¦¨¤À¤¤¬¡¤Æ PPAR£\ ®ÄªG¤§±´°Q¡C¤¤µØ¥Á°êÀç¾i¾Ç·| 29 ©¡¦~·| ¤¤µØÀç»x Vol.28. No.2, p33, 6¤ë, ¥x¥_

³\¬Àµ×¡B¶À«C¯u* (2003) °ªªo¯×¶¼­¹´£°ª Wistar ¤j¹«»P C57BL/6J ¤p¹« PPAR£\ ¬ÛÃö°ò¦]ªí²{¡C¤¤µØ¥Á°êÀç¾i¾Ç·| 29 ©¡¦~·| ¤¤µØÀç»x Vol.28. No.2, p35, 6 ¤ë, ¥x¥_

Che-Yi Chao and Ching-jang Huang* (2004) Bitter Gourd Extract Up-regulates mRNA expression of PPARƒÑƒzƒnPPARƒ× and Some of their Target Genes in Mice. Keystone Symposium. Nuclear Receptors: Orphan Brothers (J7) February 28 ¡V Mar 4, Keystone, Colorado, USA

Shu, C and Huang, C.j* (2005) Fractionation and Identification of PPAR£\ activators in the oxidized frying oil. Keystone Symposium. PPAR/LXR (Z2), April 12 - 17, 2005, Fairmont Chateau Whistler,  Whistler, British Columbia, Canada.

C Hsu, P-M Chao, Y-H Kuo and C-j Huang*¡]2005¡^Fractionation and Identification of PPAR£\ activators in the oxidized frying oil. 18th International Congress of Nutrition, September 19-23, 2005, Durban, South Africa.

SC Hsu, C-J Huang* (2005) Up-regulated PPAR£\ and SREBP/1C Related Gene Expression in High Saturated Fat Diet-induced Obesity. 18th International Congress of Nutrition, September 19-23, 2005, Durban, South Africa.

W-Y Cheng, C Huang* (2005) Increased Apparent Sodium and Potassium Retention in Rats Fed  Oxidized Frying Oil Diets. 18th International Congress of Nutrition, September 19-23, 2005, Durban, South Africa.

Mei-Ling Chang and Ching-jang Huang*. Prevention of Metabolic Syndrome in Mice Fed a Bitter Melon (Momordica charantia) containing diet. 10th Asian Congress of Nutrition, Taipei, 2007.09

Wei-Yi Cheng, Yueg-Hsiung Kuo, and Ching-jang Huang*. Isolation and Identification of Estrogenic Compounds in Yam Tuber(Dioscorea alata cv. Tainung No.2). 10th Asian Congress of Nutrition, Taipei, 2007.09

Meng-ting Wu, Yung-ju Chen, and Ching-jang Huang*. Screening of Chinese Herbal Extracts with Estrogenic Activity. 10th Asian Congress of Nutrition, Taipei, 2007.09

Yi-Jen Li, Sheng-Ching Luo, Chi-Cheng Cheng, Fu-Jung Lin, Yi-Jing Lee and Ching-jang Huang*. Identification of -CHEC sulphate conjugates as major ¡Vtocopherol metabolites in rat urine and an HPLC-ECD method for the determination of ¡VCHEC. 10th Asian Congress of Nutrition, Taipei, 2007.09

Shan-Ching Hsu and Ching-jang Huang*. Rats Fed a High Butter Diet are More Prone to Obesity and Glucose Intolerance Than Those Fed a High Safflower Oil Diet. 10th Asian Congress of Nutrition, Taipei, 2007.09

Wei-Yi Cheng, Yueg-Hsiung Kuo and Ching-jang Huang*, "Isolation and Identification of Estrogenic Compounds in Yam Tuber (Dioscorea alata cv. Tainung No.2)," 10th European nutrition conference, Paris, 2007.07

Yung-ju Chen; Meng-ting Wu; Ching-jang Huang*. Screening of Chinese herbal extracts with estrogenic activity. 10th European nutrition conference, Paris, 2007.07

¾GÞ³©y, ¶À«C¯u*, "°w¹ï°±¸g«á°ü¤k«O°·¤§¥\¯à©Ê­¹«~¦¨¤À¶}µo," °ê¬ì·|¤T¦~­pµe¾À³øµoªí, ®ü¬v¤j¾Ç, 2006.11

Wei-Yi Cheng and Ching-jang Huang*, "INCREASED APPARENT SODIUM  AND POTASSIUM RETENTION IN RATS FED OXIDIZED FRYING OIL DIETS.," ²Ä¤Q¤K©¡°ê»ÚÀç¾i¦~·|, «n«D, 2005.09

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Book Chapters

Ching-jang Huang (1999) The nutritional and physiological effects of feeding deep-frying oil. p149-154. In Proceedings of 8th Congress of Nutrition, Korean Nutrition Society /Federation of Asian Nutrition Societies. p149-154

Ching-jang Huang (2003) Prostaglandin formation as affected by dietary frying oil and other food components. In: Essential Fatty Acids and Eicosanoids: Invited Papers from the Fifth International Congress. AOCS Press

C Hsu, PM Chao, YH Kuo and C-j Huang (2005) Fractionation and identification of ppar£\ activators in the oxidized frying oil. AnnaIs of Nutrition & Metabolism, Proceedings of 18th Congress of Nutrition, Kargers. (on a CD ROM) (ISBN: 3-8055-8015-0)

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Patents

2006¦~ Compounds having estrogenic activity (US, 11/673,433) in application

2007¦~ Process For Preparation Of Aglucone Isoflavones in application

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Publication  1998~2007

Referred Paper

Huang, C.J., Feltkamp, D., Nilsson, S. and Gustafsson, J.A. (1998) Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signaling. Biochem. Biophys. Res. Commun. 243: 657-663

Shaw, H.M. and Huang, C.J. (1998) Liver alpha-tocopherol transfer protein and its mRNA were differentially altered by dietary vitamin E deficiency and protein insufficiency in rats. J. Nutr., 128: 2348-2354

Tang, Y.L. and Huang, C.J. (1998) Dientary Oxidized Frying Oil Decreased Plasma and Liver Vitamin A in Rats. Nutr. Sci. J. 23 (3): 265-279

Chu, C.H. and Huang, C.J. (1998) Dientary Oxidized Frying Oil Compromised Vitamin A Value of £]-Carotene in Rats. Nutr. Sci. J. 23 (3): 281-295

Huang, C.j., Tang, Y.L., Chen, C.Y., Chen, M.L., Chu, C.H & Hseu, C.T. (2000) The bioavailability of b-carotene in stir- or deep-fried vegetables determined by measuring serum response to a single ingestion in men. J. Nutr. 130: 534-540

Shaw, H.M. and Huang, C.j. (2000) Secretion of a-tocopherol in VLDL was decreased by dietary protein insufficiency in young growing rats. J. Nutr. 130: 3050-3054

Cheng, A.L., Pan, T.M., Hung, H.P., Huang, C.J. (2000) Intestinal Microflora is Improved by the Feeding of an Oligosaccharide Containing Soft Drink in Rats. Nutr. Sci. J., 25 (4): 233-243

Wu, M.C. and Huang, C.j. (2001) Inhibition of prostaglandin E2 production of a macrophage cell line by some phytochemicals. Fd. Sci. Agric. Chem. 3: 59-71

Chao, P.M., Huang, C.J. (2001) Effect of 15-deoxy-£G12,14-PGJ2 to 3T3-L1 Preadipocytes into Adipocytes. J. Chin. Med. Sci., 2 (2): 117-124

Chao, P.M., Chao, C.Y., Lin, F.J. and Huang, C.j. (2001) Oxidized frying oil up-regulates hepatic acyl CoA oxidase and cytochrome P-450 4A1 genes in rats and activate PPAR-a. J.Nutr.131: 3166-3174

Wu, M.C. and Huang, C.j. (2002) Differential effects of foods traditional regarded as heating and cooling on prostaglandin E2 production by a macrophage cell line. J. Biomed. Sci. 9: 596-606

Liu, J.F., Yang, F.L., Wang, T.Y., Cheng, C.M., Shaw N.S., Kao, M.D., Chuang, C.Y., Huang, C.J. (2002) Analysis of Vitamine E, Selenium, and Other Nutrients in Planned Balanced Diets in Taiwan. Nutr. Sci. J., 27 (4): 221-231

Chao, C.Y. and Huang, C.-j (2003) Bitter gourd (Momordica charantia) extract activates PPAR and up-regulates the expression of acyl CoA oxidase gene in H4IIEC3 hepatoma cells. J Biomed Sci 10: 782-791

Chao, P.M., Hsu, S.C., Lin, F.J., Li, Y.J. and Huang, C.j (2004) The up-regulation of hepatic acyl-CoA oxidase and cytochrome  P450 4A1 mRNA expression by dietary oxidized frying oil is comparable between male and female rats. Lipids: 39: 233-238

Lin, S.Y., Chen W.Y., Lee F.Y., Huang, C.j., and Sheu, W.H.H. (2005) Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-a. Am J Physiol Endocrinol Metab 288: E493-E501

Lin, S.Y., Sheu, W.H.H., Chen W.Y., Lee F.Y., Huang, C.j. (2005) Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha. Mol. Cell. Endocrinol. 232: 1¡V8

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang, C.j. (2005)  Plasma Retinol and £\-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asian Pacific J. Clin. Nutr. 14(3): 256-262

Chao, P.M., Yang, M.F., Tseng, Y.N., Chang, K.M., Lu, K.S., Huang, C.j. (2005) Peroxisome proliferation in liver of rats fed oxidized frying oil. J. Nutr. Sci. Vitaminol. 51: 361-368

Lin, S.Y., Chen W.Y., Lee F.Y., Huang, C.j., and Sheu, W.H.H. (2005) Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-. Am J Physiol Endocrinol Metab 288: E493-E501

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang*, C-j. (2005)  Plasma Retinol and \-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asia Pac J Clin Nutr 2005; 14 (3):256-262

Chao, P.M., Yang, M.F., Tseng, Y.N., Chang, K.M., Lu, K.S., Huang*, C.-j. (2005) Peroxisome proliferation in liver of rats fed oxidized frying oil. J. Nutr. Sci. Vitaminol. 51: 361-368

Cheng, W-Y, Fu, M-L, Wen, L-J, Chen C., Pan, W-H, Huang*, C-j. (2005)  Plasma Retinol and \-Tocopherol Status of Taiwanese Elderly Population: NAHSIT II, 1999-2001. Asia Pac J Clin Nutr 2005; 14 (3):256-262

Hsieh, C.C., Huang, C-j and Lin, B.F.*(2006) Low and high levels of -tocopherol exert opposite effects on IL-2 possibly through the modulation of PPAR, IkB and apoptotic pathway in activated splenocytes. Nutrition 22 (4): 433-440.

Hsu, S-C, Huang, C.-j*. (2006) Changes of Liver PPAR mRNA Expression in Response to two levels of high safflower oil diets Correlate with Changes of Adiposity and serum leptin in rats and mice. J. Nutr. Biochem. (Published on-line)

Hsu, S-C, Huang, C.-j*. (2006) Reduced fat mass in rats fed a high oleic acid-rich safflower oil diet is associated with changes in expression of hepatic PPAR alpha and adipose SREBP-1c-regulated genes. J. Nutr. 1779-1785

Chia-Ying Chuang1, Chin Hsu1, Che-Yi Chao1, Yung-Shung Wein2, Yueh-Hsiung Kuo2, Ching-jang Huang (2006) Fractionation and Identification of 9c, 11t, 13t- Conjugated Linolenic Acid as an Activator of PPARalpha in Bitter Gourd (Momordica charantia L.)  J Biomed Sci. 13(6):763-72.

Lun-Cheng Kuo1, Wei-Yi Cheng1, Ren-Yu Wu1, Ching-Jang Huang1 and Kung-Ta Lee]2006^Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto. Applied Microbiology and Biotechnology 73(2):314-320.

Hsu, S-C, Huang, C.-j*. (2007) Changes of Liver PPARa mRNA Expression in Response to two levels of high safflower oil diets Correlate with Changes of Adiposity and serum leptin in rats and mice. J. Nutr. Biochem. 18(2), 86-96.

Pei-Min Chao, Hui-Ling Huang, Chun-Huei Liao, Shiau-Ting Huang, and Ching-jang Huang(2007) A high oxidized frying oil content diet is less adipogenic, but induces glucose intolerance in rodents. Brit. J. Nutr. Accepted

Book

Ching-jang Huang (1999) The nutritional and physiological effects of feeding deep-frying oil. p149-154. In Proceedings of 8th Congress of Nutrition, Korean Nutrition Society /Federation of Asian Nutrition Societies. p149-154

Ching-jang Huang (2003) Prostaglandin formation as affected by dietary frying oil and other food components. In: Essential Fatty Acids and Eicosanoids: Invited Papers from the Fifth International Congress. AOCS Press

C Hsu, PM Chao, YH Kuo and C-j Huang (2005) Fractionation and identification of ppar£\ activators in the oxidized frying oil. AnnaIs of Nutrition & Metabolism, Proceedings of 18th Congress of Nutrition, Kargers. (on a CD ROM) (ISBN: 3-8055-8015-0)

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Important Results

Basic and applied research

 

(A)

(B)

 

(C) 

 (D)

(E)

 

¡¶ Estrogenic Compounds Isolated from Dioscorea Alata (TN2) and the dose-dependent Transactivation of Estrogen Receptor £\ and Estrogen Receptor £]. (A) RRR-£\-tocopherol (B) Hydro-Q9 Chromene (C) £^-tocopherol 9 (D) Coenzyme Q9 (E) 1-Feruloyl glycerol. (B) and (C) are Novel Compounds.

 

(A)                PPAR£\  Transactivation

 

(B)                 H4¢ºEC3  hepatoma cell line

 

¡¶ 9c, 11t, 13t-conjugated linolenic acid was isolated and identified from wild bitter ground as the activator of PPAR£\. (A) Dose-dependent Transactivation of PPAR£\. (B) Dose-dependent of Acyl CoA oxidase in H4¢ºEC3 hepatoma cells. J Biomed Sci 2006;13(6):763-772.

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Last updated: 2008/09/13